The reference site for Doxazosin

Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an α1-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia (BPH).

WHAT IS DOXAZOSIN?

Doxazosin is an inhibitor of the alpha 1 adrenergic nervous system. It is in a class of drugs referred to as alpha blockers. Elevated blood pressure is lowered as the action of these nerves, which promote constriction of blood vessels, is blocked.

This medication is used for the control of elevated blood pressure and for benign prostatic hyperplasia.

Doxazosin was also found to relax the muscles around the prostate gland which is also under the influence of the alpha adrenergic portion nervous system. This can makes urination easier for men affected by enlarged prostate glands.

 

Brand Name(s): Cardura
CAS nº: 74191-85-8
(dox ay’ zoe sin)

 

Product Info

The sections below will provide you with more specific information and guidelines related to doxazosin and its correct use. Please read them carefully.

FDA Information

The FDA approved doxazosin in 1995.

On February 28th 2006, the FDA approved safety labeling revisions for doxazosin mesylate tablets (Cardura®, made by Pfizer Inc.) to warn of the risk for intraoperative floppy iris syndrome during cataract surgery in patients receiving or previously treated with this or other alpha-1 blockers.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Doxazosin is used for the control of elevated blood pressure (hypertension) and for benign prostatic hyperplasia (noncancerous enlargement of the prostate gland).

Doxazosin is an inhibitor of the alpha 1 adrenergic nervous system. It is in a class of drugs referred to as alpha blockers that includes alfusosin (Uroxatral®), terazosin (Hytrin®), tamsulosin (Flomax®), and prazosin (Minipress®). Elevated blood pressure (hypertension) is lowered as the action of these nerves, which promote constriction of blood vessels, is blocked.

Doxazosin was also found to relax the muscles around the prostate gland which is also under the influence of the alpha adrenergic portion nervous system. This can makes urination easier for men affected by enlarged prostate glands.

Other uses for this medicine

Doxazosin is sometimes used in combination with other medications to treat congestive heart failure.

However, it is important that you first of all talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Doxazosin comes as a tablet, which is to be administered orally. It is usually taken with or without food once a day in the morning or in the evening.

To help you remember to take doxazosin, take it around the same time every day.

Your doctor will start you on a low dose of doxazosin and gradually increase your dose, not more than once every 1 to 2 weeks. Please take doxazosin exactly as directed by your doctor. Do not take more or less of it or take it more often than prescribed by your doctor.

If you stop taking doxazosin for a few days or longer, your doctor will have to start you again on the lowest dose and gradually increase your dose.

Please note that this medication controls high blood pressure and the symptoms of BPH but does not cure them. Continue to take doxazosin even if you feel well, and never stop taking doxazosin without first talking to your doctor.

What special precautions should I follow?

BEFORE TAKING DOXAZOSIN:

Always tell your doctor and pharmacist if you are allergic to doxazosin, prazosin (Minipress®), terazosin (Hytrin®), or any other medications.

Inform your doctor and pharmacist what prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention if you are taking other medications for high blood pressure, as your doctor may need to change the doses of your medications or monitor you carefully for side effects.

Tell your doctor if you have or have ever had liver disease.

Moreover, please inform your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking doxazosin, call your doctor.

Also, if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking doxazosin.

You should know that doxazosin may make you drowsy or dizzy. Do not drive a car or operate machinery for 24 hours after the first time you take doxazosin or after your dose is increased.

Additionally, doxazosin may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking doxazosin and when your dose is increased. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. If you experience these symptoms, sit or lie down.

What should I do if I forget a dose?

Take the missed doxazosin dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. NEVER take a double dose of this medication as a double dose could cause severely low blood pressure.

If you miss doses for several days in a row, call your doctor before taking any additional doses. You may need to restart treatment on a lower dosage.

What side effects can this medication cause?

Possible side effects from doxazosin may include:

vivid dreams
dizziness or drowsiness
fatigue
nausea
vomiting
diarrhea
constipation
abdominal pain
decreased appetite
fluid retention or slight weight gain
joint or muscle aches
headache
irritability
depression
increased urination
decreased sex drive
numbness or tingling in the hands, feet, arms or legs

Tell your doctor if any of these symptoms are severe or do not go away:

dizziness
headache
tiredness
blurred vision
decreased sexual ability
nervousness
increased urination
upset stomach
vomiting
diarrhea
constipation
gas
muscle weakness or pain
ringing in ears
dry mouth
stuffy nose
difficulty sleeping
depression
flushing (feeling of warmth)

More importantly, if you experience any of the following symptoms, call your doctor immediately:

difficulty breathing
fast heartbeat
irregular heartbeat
chest pain
skin rash
swollen ankles or feet
fainting
painful erection of the penis that lasts for several hours

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Always keep this medication in the container it came in, tightly closed, and out of reach of children. Additionally, store it at room temperature and away from excess heat and moisture (not in the bathroom).

Be sure to throw away any medication that is outdated or no longer needed. If you have any questions regarding the proper disposal of your medication, please talk to your pharmacist.

In case of an emergency/overdose

In the case of a suspected overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.

Symptoms of an overdose may include:

dizziness
lightheadedness
fainting
seizure
fast pulse
loss of consciousness or coma

Product Images

PICTURES OF DOXAZOSIN PILLS

Below you will find images and specific information on the principal types of doxazosin that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: DOXAZOSIN MESYLATE
Strength(s): 1 MG
Imprint: APO | 093
Manufacturer: APOTEX CORP.

Name: DOXAZOSIN MESYLATE
Strength(s): 1 MG
Imprint: N 590 | 1
Manufacturer: TEVA USA

Name: DOXAZOSIN MESYLATE
Strength(s): 1 MG
Imprint: R 642
Manufacturer: PUREPAC PHARM.

Name: DOXAZOSIN MESYLATE
Strength(s): 2 MG
Imprint: APO | 094
Manufacturer: APOTEX CORP.

Name: DOXAZOSIN MESYLATE
Strength(s): 2 MG
Imprint: R 643
Manufacturer: PUREPAC PHARM.

Name: DOXAZOSIN MESYLATE
Strength(s): 2 MG
Imprint: M D10
Manufacturer: MYLAN

Name: CARDURA®
Strength(s): 2 MG
Imprint: CARDURA | 2 mg
Manufacturer: PFIZER US PHARM.

Name: DOXAZOSIN MESYLATE
Strength(s): 4 MG
Imprint: PLIVA 653
Manufacturer: PLIVA INC.

Name: CARDURA®
Strength(s): 4 MG
Imprint: CARDURA | 4 mg
Manufacturer: PFIZER US PHARM.

Name: DOXAZOSIN MESYLATE
Strength(s): 4 MG
Imprint: APO | 095
Manufacturer: APOTEX CORP.

Name: DOXAZOSIN MESYLATE
Strength(s): 4 MG
Imprint: R 644
Manufacturer: PUREPAC PHARM.

Name: CARDURA®
Strength(s): 8 MG
Imprint: CARDURA | 8 mg
Manufacturer: PFIZER US PHARM.

Name: DOXAZOSIN MESYLATE
Strength(s): 8 MG
Imprint: APO | 960
Manufacturer: APOTEX CORP.

Name: DOXAZOSIN MESYLATE
Strength(s): 8 MG
Imprint: N 598 | 8
Manufacturer: TEVA USA

Contact us